MapQuest Driving Directions to Kotzebue, AK. Kotzebue (/ Ë k É t s É b j uË / KOTS-É-bew) or QikiqtaÄ¡ruk (/ k ɪ k ɪ k Ë t Ê É¡ r Ê k / kik-ik-TUG-rook, Inupiaq: [qekeqtÉÊÊuk]) is a city in the Northwest Arctic Borough in the U.S. state of Alaska.It is the ⦠Distance from Anchorage to Kotzebue (Ted Stevens Anchorage International Airport â Ralph Wien Memorial Airport) is 548 miles / 883 kilometers / 477 nautical miles. Get to know the cheapest flight price, number of direct flights between Kotzebue and Anchorage, how many flights between Kotzebue and Anchorage per week, distance and flight duration from Kotzebue to Anchorage and the number of airports in Anchorage [Note: The distance between cities in Alaska (US) distance chart below is straight line distance (may be called as flying or air distance⦠Distance from Kotzebue, AK to Anchorage, AK. Friday has the greatest variety of flight times for Anchorage to Kotzebue â¦